Author

P. Kelly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Bezuidenhout· 1 shared A. Costello· 1 shared A. Cox· 1 shared A. J. Toepp· 1 shared A. Kumar Kushwaha· 1 shared A. Leal Lima· 1 shared B. M. Scorza· 1 shared B. Markey· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Bezuidenhout

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Unveiling the Role of Endoplasmic Reticulum Stress Pathways in Canine Demodicosis

P. Kelly, G. P. McHugo, C. Scaife, S. Peters, M. L. Stevenson, J. S. McKay, D. E. MacHugh, I. Lara-Saez, R. Breathnach

This study identifies endoplasmic reticulum stress pathways as contributors to canine demodicosis through immunosuppressive mechanisms involving M2 macrophages and TLR2 modulation.

bioRxiv · Aug 11, 2023Immunology

Leishmania infantum xenodiagnosis from vertically infected dogs reveals significant skin tropism

B. M. Scorza, K. G. Mahachi, A. Cox, A. J. Toepp, A. Leal Lima, A. Kumar Kushwaha, P. Kelly, C. Menenses, G. Wilson, K. Gibson-Corley, L. Bartholomay, S. Kamhawi, C. A. Petersen

This study shows vertically infected dogs transmit Leishmania infantum to sand flies more effectively when they have moderate disease, with higher skin parasite loads correlating strongly with sand fly infection.

bioRxiv · Apr 8, 2021Microbiology

West Nile virus in crocodiles and mosquitoes in Zimbabwe

M. Roy, F. Mufunda, D. Slawski, C. Mutswiri, I. Mvere, K. Slawski, P. Kelly, A. Bezuidenhout, I. Piras, T. Hanyire, B. Markey, G. Barry

The paper detects West Nile virus lineages 1 and 2 in Zimbabwean mosquitoes and crocodile samples, indicating viral circulation and potential risk to humans and animals.

bioRxiv · Feb 19, 2021 · PreprintMicrobiology

Sub physiological temperature induces pervasive alternative splicing in Chinese hamster ovary cells

I. Tzani, C. Monger, K. Motheramgari, C. Gallagher, R. Hagan, P. Kelly, A. Costello, J. Meiller, P. Floris, L. Zhang, M. Clynes, J. Bones, N. Barron, C. Clarke

This study shows that reducing temperature induces widespread alternative splicing in CHO cells, with many events occurring in genes not detected by standard expression analysis.

bioRxiv · Dec 3, 2019Cell Biology

Targeting tRNA-Synthetase Interactions towards Novel Therapeutic Discovery Against Eukaryotic Pathogens

P. Kelly, F. Hadi-Nezhad, D. Liu, T. J. Lawrence, R. J. Linington, M. Ibba, D. H. Ardell

This paper identifies parasite-specific tRNA-synthetase interactions as a target for broad-spectrum anti-trypanosomal drugs, validated through natural product inhibitors with no human homolog activity.

bioRxiv · Jul 23, 2019Microbiology