BiophysicsbioRxivPreprint
Complexes of tubulin oligomers and tau form an intervening network cross-bridging microtubules into bundles
P. Kohl, C. Song, B. J. Fletcher…·C. R. Safinya
The paper identifies an intervening network of tubulin-tau complexes that cross-link microtubules into bundles, revealing a new role for tubulin in stabilizing MT fascicles and preventing tau leakage in neurodegeneration.
DOI 10.1101/2022.07.18.500499