C. R. Safinya

This study investigates how multivalent cationic lipid MVL5 and PEG-lipids affect the structure of fluid lipid assemblies, revealing distinct morphologies like discs, rods, and spheres.

This study shows that increasing PEG coverage on cationic lipid nanoparticles improves their tumor penetration and proapoptotic activity when delivering paclitaxel.

The paper identifies an intervening network of tubulin-tau complexes that cross-link microtubules into bundles, revealing a new role for tubulin in stabilizing MT fascicles and preventing tau leakage in neurodegeneration.

This study shows that replacing oleoyl with linoleoyl lipid tails in cationic liposomes increases paclitaxel solubility, enhancing cancer therapeutic efficacy without increasing toxicity.

This study investigates how peptide density and charge affect the binding and uptake of cationic liposome-DNA nanoparticles by cancer cells and evaluates their tumor selectivity in vivo.

This paper investigates the solubility and cytotoxicity of paclitaxel-loaded cationic liposomes at different drug contents, revealing nonmonotonic efficacy patterns linked to kinetic phase behavior.