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2 papers
Recent·Most cited
B. T. Emmer, P. J. Lascuna, E. Kotnik, T. Saunders, R. Khoriaty, D. Ginsburg
This study shows that Surf4 is essential for early embryonic development in mice, as Surf4-/- embryos die between E3.5 and E9.5, while Surf4+/- mice are normal.
bioRxiv · Feb 7, 2019Cell Biology
B. T. Emmer, G. G. Hesketh, E. Kotnik, V. T. Tang, P. J. Lascuna, J. Xiang, A.-C. Gingras, X.-W. Chen, D. Ginsburg
This study identifies SURF4 as a cargo receptor that facilitates PCSK9 secretion by linking it to COPII components and confirming its functional role through multiple experimental approaches.
bioRxiv · May 31, 2018Cell Biology