Author

P. J. Roy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Pharmacology & Toxicology· 3

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3

Frequent Co-Authors

J. Knox· 2 shared A. Burns· 1 shared A. R. Burns· 1 shared D. H. Hall· 1 shared D. Han· 1 shared D. Kulke· 1 shared D. L. Bar-Yosef· 1 shared E. Gazit· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPharmacology & Toxicology

J. Knox

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Author profile →

3 papers

Recent·Most cited

Nemacol is a Small Molecule Inhibitor of C. elegans Vesicular Acetylcholine Transporter with Anthelmintic Potential

S. Harrington, J. Pyche, A. R. Burns, T. Spalholz, R. J. Baker, J. Ching, M. Lautens, D. Kulke, W. Deuther-Conrad, P. Brust, P. J. Roy

A small molecule screen identifies a vesicular acetylcholine transporter inhibitor scaffold that incapacitates parasitic nematodes.

bioRxiv · Jun 14, 2022 · PreprintPharmacology & Toxicology

A Rapid in vivo Pipeline to Identify Small Molecule Inhibitors of Amyloid Aggregation

M. Kamal, J. Knox, R. I. Horne, O. S. Tiwari, A. Burns, D. Han, D. L. Bar-Yosef, E. Gazit, K. C. Nguyen, D. H. Hall, M. Vendruscolo, P. J. Roy

This paper presents an in vivo pipeline to identify small molecule inhibitors of amyloid aggregation by screening compounds that suppress crystal formation in C. elegans.

bioRxiv · Apr 11, 2022 · PreprintPharmacology & Toxicology

A Survey of the Kinome Pharmacopeia Reveals Multiple Scaffolds and Targets for the Development of Novel Anthelmintics

J. Knox, W. Zuercher, P. J. Roy

The paper identifies nematode-specific kinase targets and small molecule scaffolds for developing novel anthelmintics by screening vertebrate kinase inhibitors in C. elegans.

bioRxiv · Aug 20, 2020Pharmacology & Toxicology