P. J. Skene

The study identifies age-related differences in naive T cell compartments between children and adults, showing distinct molecular reprogramming in CD4 and CD8 subsets.

Serum proteome profiling identifies subsets of long COVID patients with evidence of persistent inflammation and key immune signaling pathways.

The paper profiles longitudinal immune responses in mild COVID-19 patients to identify recovery and persistence signatures.

This study shows that delayed blood processing causes significant changes in single-cell transcriptomes and plasma proteomes within 6 hours, potentially confounding disease-related biological variance.

The paper introduces TEA-seq, a trimodal assay that integrates scRNA-seq, cell surface epitopes, and scATAC-seq to improve single-cell analysis of transcription, epitopes, and chromatin accessibility.