Author

J. Reading

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:scRNA-seq· 4 Research Focus:cell type annotation· 3 Approach:deep learning· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:transcription & RNA processing· 2

Frequent Co-Authors

L. T. Graybuck· 4 shared T. R. Torgerson· 4 shared A. K. Savage· 3 shared A. T. Heubeck· 3 shared E. Swanson· 3 shared P. J. Skene· 3 shared S. V. Vasaikar· 3 shared T. F. Bumol· 3 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

L. T. Graybuck

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Author profile →

5 papers

Recent·Most cited

PALMO: a comprehensive platform for analyzing longitudinal multi-omics data

S. V. Vasaikar, A. K. Savage, Q. Gong, E. Swanson, A. Talla, C. Lord, A. Heubeck, J. Reading, L. T. Graybuck, P. Meijer, T. R. Torgerson, P. Skene, T. Bumol, X.-j. Li

PALMO analyzes longitudinal multi-omics data by decomposing variations, identifying stable/variable features, and detecting markers across timepoints, validated on a complex dataset and external benchmarks.

bioRxiv · Oct 17, 2022 · PreprintImmunology

Distinct Heterogeneity in the Naive T cell Compartments of Children and Adults

C. E. Gustafson, Z. Thomson, Z. He, E. Swanson, K. Henderson, M.-P. L. Pebworth, L. Y. Okada, A. T. Heubeck, C. R. Roll, V. Hernandez, M. D. Weiss, P. C. Genge, J. Reading, J. R. Giles, S. Manne, , P. J. Skene

The study identifies age-related differences in naive T cell compartments between children and adults, showing distinct molecular reprogramming in CD4 and CD8 subsets.

bioRxiv · Oct 4, 2022 · PreprintImmunology

Longitudinal immune dynamics of mild COVID-19 define signatures of recovery and persistence

A. Talla, S. V. Vasaikar, M. P. Lemos, Z. Moodie, M.-P. L. Pebworth, K. E. Henderson, K. W. Cohen, J. L. Czartoski, L. Lai, M. S. Suthar, A. T. Heubeck, P. C. Genge, C. R. Roll, M. Weiss, J. Reading, , T. F. Bumol

The paper profiles longitudinal immune responses in mild COVID-19 patients to identify recovery and persistence signatures.

bioRxiv · May 26, 2021 · PreprintImmunology

TEA-seq: a trimodal assay for integrated single cell measurement of transcription, epitopes, and chromatin accessibility

E. Swanson, C. Lord, J. Reading, A. T. Heubeck, A. K. Savage, R. Green, X.-j. Li, T. R. Torgerson, T. F. Bumol, L. T. Graybuck, P. J. Skene

The paper introduces TEA-seq, a trimodal assay that integrates scRNA-seq, cell surface epitopes, and scATAC-seq to improve single-cell analysis of transcription, epitopes, and chromatin accessibility.

bioRxiv · Sep 4, 2020 · PreprintImmunology

Escape from nonsense mediated decay associates with anti-tumor immunogenicity

K. Litchfield, J. Reading, E. Lim, H. Xu, P. Liu, M. Al-Bakir, S. Wong, A. Rowan, S. Funt, T. Merghoub, M. Lauss, I. M. Svane, G. Jonsson, J. Herrero, J. Larkin, , C. Swanton

This study identifies NMD-escape fs-indels as a biomarker associated with improved response to immunotherapy in melanoma patients.

bioRxiv · Nov 14, 2019Cancer Biology