Author

P. Kannouche

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. A. Yurchenko· 1 shared A. Allouch· 1 shared A. Lehmann· 1 shared A. Sarasin· 1 shared A.-A. Muhammad· 1 shared B. S. Lopez· 1 shared C. F. M. Menck· 1 shared C. Nishigori· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. A. Yurchenko

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2 papers

Recent·Most cited

Analysis of Skin Cancers from Xeroderma Pigmentosum Patients Reveals Heterogeneous UV-Induced Mutational Profiles Shaped by DNA Repair

A. A. Yurchenko, F. Rajabi, T. Braz-Petta, H. Fassihi, A. Lehmann, C. Nishigori, I. Padioleau, K. Gunbin, L. Panunzi, F. Morice-Picard, P. Laplante, C. Robert, P. Kannouche, C. F. M. Menck, A. Sarasin, S. I. Nikolaev

The paper analyzes skin cancer genomes from Xeroderma Pigmentosum patients to show how NER activity shapes mutation rates and reveals POLH's role in bypassing UV-induced DNA lesions.

bioRxiv · Oct 14, 2022 · PreprintCancer Biology

In vivo inactivation of RAD51-mediated homologous recombination leads to premature aging, but not to tumorigenesis

G. Matos-Rodrigues, V. Barroca, A.-A. Muhammad, A. Allouch, S. Koundrioukoff, D. Lewandowski, E. Despras, J. Guirouilh-Barbat, L. Frappart, P. Kannouche, P. Dupaigne, E. Le Cam, J.-L. Perfettini, P.-H. Romeo, M. Debatisse, , B. S. Lopez

This study shows that inactivating RAD51 in mice causes premature aging but not cancer, suggesting RAD51 is critical for progenitor cell homeostasis.

bioRxiv · Jan 17, 2022 · PreprintCancer Biology