j.-l. PERFETTINI

This study shows that AGuIX nanoparticles and their combination with ionizing radiation induce proinflammatory reprogramming of tumor-associated macrophages via AMPK-dependent mitochondrial fragmentation.

This study identifies P2X7 and NLRP3 inflammasome as host factors required for SARS-CoV-2 infection and shows their role in promoting viral replication.

This study shows that overexpressing CDKN1A in macrophages enhances their ability to phagocytose leukemic cells, leading to pro-inflammatory reprogramming and improved survival in mouse models.

This study shows that inactivating RAD51 in mice causes premature aging but not cancer, suggesting RAD51 is critical for progenitor cell homeostasis.