A novel combination of chemotherapy and immunotherapy controls tumor growth in mice with a human immune system
A. Burlion, R. Ramos, K. Sendeyo, P. KC, A. Corneau, C. Caux, E. Piaggio, D. Olive, C. Caux, G. Marodon
This study shows that combining anti-ICOS mAb with chemotherapy reduces tumor growth in humanized mice by enhancing CD8+ T cell activity and reducing Treg numbers.
bioRxiv · Jan 3, 2019Immunology