Author

P. Klemm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

A. C. Hausen· 1 shared A. Jais· 1 shared A. Josephrajan· 1 shared A. Pfeifer· 1 shared A. R. A. d. A. Tavanez· 1 shared A. Rada-Iglesias· 1 shared A. Sieben· 1 shared B. D. M. Larsen· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. C. Hausen

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cold-induced expression of a truncated Adenylyl Cyclase 3 acts as rheostat to brown fat function.

S. Khani, H. Topel, A. Josephrajan, B. D. M. Larsen, A. R. A. d. A. Tavanez, M. J. Gaudry, P. Leyendecker, N. Stanic, I. Gaziano, N. R. Hansmeier, E. Schmidt, P. Klemm, L.-M. Vagliano, C. A. Engelhard, S. Nielsen, , J.-W. Kornfeld

The paper identifies a cold-inducible truncated Adcy3 mRNA isoform, Adcy3-at, which acts as a rheostat to regulate brown fat function by limiting cAMP activity during obesity.

bioRxiv · Aug 1, 2022Cell Biology

P2Y6 receptor signaling in natural killer cells impairs insulin sensitivity in obesity

A. Sieben, A. C. Hausen, P. Klemm, A. Jais, C. Heilinger, J. Alber, K. Folz-Donahue, L. Schumacher, J. Altmüller, M. Franitza, P. Giavalisco, Y. Hinze, S. Brodesser, C. Kukat, S. Theurich, J. C. Brüning

This study shows that blocking P2Y6R in NK cells improves insulin sensitivity in obese mice by reducing adipose tissue inflammation and glucose production.

bioRxiv · Jun 23, 2021 · PreprintImmunology