Author

S. Khani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Bartelt· 2 shared C. Jethwa· 2 shared S. Herzig· 2 shared S. Kotschi· 2 shared A. Ghosh· 1 shared A. Hoffmann· 1 shared A. Josephrajan· 1 shared A. Mena Gomez· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersPhysiology

A. Bartelt

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Control of cholesterol-induced adipocyte inflammation by the Nfe2l1-Atf3 pathway

C. Jethwa, A. Hoffmann, S. Kotschi, J. Caesar, M. Kern, A. Worthmann, C. Schlein, S. Khani, B. A. Arus, O. T. Bruns, A. Ghosh, C. Wolfrum, Y. Döring, S. Herzig, C. Weber, , A. Bartelt

This study identifies the Nfe2l1-Atf3 pathway as a regulator of cholesterol-induced adipocyte inflammation and insulin resistance in both human and mouse models.

bioRxiv · Jul 22, 2024 · PreprintPhysiology

The myocyte Nfe2l1-ubiquitin-proteasome system controls muscle fiber type and obesity-induced insulin resistance

I. L. Lemmer, D. T. Haas, N. Willemsen, S. Kotschi, I. Toksoez, E. Gjika, S. Khani, M. Rohm, N. Diercksen, P. B. H. Nguyen, M. P. Menden, D. T. Egu, J. Waschke, S. Larsen, T. Ma, , A. Mena Gomez

This study shows that Nfe2l1 regulates skeletal muscle proteostasis and function, with its loss causing muscle fiber type switching and insulin resistance in high-fat diet conditions.

bioRxiv · Apr 20, 2023 · PreprintPhysiology

Cold-induced expression of a truncated Adenylyl Cyclase 3 acts as rheostat to brown fat function.

S. Khani, H. Topel, A. Josephrajan, B. D. M. Larsen, A. R. A. d. A. Tavanez, M. J. Gaudry, P. Leyendecker, N. Stanic, I. Gaziano, N. R. Hansmeier, E. Schmidt, P. Klemm, L.-M. Vagliano, C. A. Engelhard, S. Nielsen, , J.-W. Kornfeld

The paper identifies a cold-inducible truncated Adcy3 mRNA isoform, Adcy3-at, which acts as a rheostat to regulate brown fat function by limiting cAMP activity during obesity.

bioRxiv · Aug 1, 2022Cell Biology