Cell BiologybioRxiv
Cold-induced expression of a truncated Adenylyl Cyclase 3 acts as rheostat to brown fat function.
S. Khani, H. Topel, A. Josephrajan…·J.-W. Kornfeld
The paper identifies a cold-inducible truncated Adcy3 mRNA isoform, Adcy3-at, which acts as a rheostat to regulate brown fat function by limiting cAMP activity during obesity.
DOI 10.1038/s42255-024-01033-8