Author

P. Lindholm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

A. Eesmaa· 1 shared D. R. Vera· 1 shared E. Ashworth· 1 shared E.-P. Kumpula· 1 shared I. B. Antunes· 1 shared J. Huiskonen· 1 shared J. Nam· 1 shared J. Neves· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCell Biology

A. Eesmaa

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3 papers

Recent·Most cited

A novel method for tracking nitrogen kinetics in vivo and ex vivo using radioactive nitrogen-13 gas and Positron Emission Tomography

E. Ashworth, R. Ogawa, D. R. Vera, P. Lindholm

This study develops a PET-based method to track nitrogen gas movement in vivo and ex vivo using 13N2, showing its distribution in organs after inhalation.

bioRxiv · Jun 1, 2023Physiology

Ageing disrupts MANF-mediated immune modulation during skeletal muscle regeneration

N. S. Sousa, M. F. Bras, I. B. Antunes, P. Lindholm, J. Neves, P. Sousa-Victor

This study identifies MANF as a critical immune modulator for skeletal muscle regeneration, showing its loss in aged mice impairs regeneration and can be mitigated by MANF delivery.

Nature Aging · Mar 23, 2023Peer-reviewedCell Biology

MANF regulates unfolded protein response and neuronal survival through its ER-located receptor IRE1α

V. Kovaleva, L.-Y. Yu, L. Ivanova, J. Nam, A. Eesmaa, E.-P. Kumpula, J. Huiskonen, P. Lindholm, M. H. Voutilainen, M. Karelson, M. Saarma

This study identifies MANF's mechanism of action through its interaction with IRE1α, showing it modulates UPR and protects neurons from ER stress.

bioRxiv · Sep 22, 2020 · PreprintCell Biology