Author

L. Ivanova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

M. Karelson· 2 shared M. Saarma· 2 shared A. Eesmaa· 1 shared B. G. Butt· 1 shared B. Sulkow· 1 shared B. Wu· 1 shared C. Jeffries· 1 shared C. M. Crump· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersPharmacology & Toxicology

M. Karelson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Novel RNA m6A methyltransferase METTL16 inhibitors

S. Selberg, L. Ivanova, M. Kotli, K. Herodes, D. Blokhina, E. Kankuri, N. Seli, I. Ilves, I. Teino, M. Saarma, M. Karelson

This study identifies two nanomolar METTL16 inhibitors that reduce leukemia cell viability and m6A levels in HL-60 cells.

bioRxiv · Mar 27, 2023 · PreprintPharmacology & Toxicology

Maximum Antigen Diversification in a Lyme Bacterial Population and Evolutionary Strategies to Overcome Pathogen Diversity

L. Di, S. Akther, E. Bezrucenkovas, L. Ivanova, B. Sulkow, B. Wu, M. Gomes-Solecki, W. Qiu

The paper shows evolution-based synthetic antigen designs can overcome pathogen diversity by generating broadly reactive OspC analogs against Lyme disease strains.

bioRxiv · Dec 16, 2020Microbiology

MANF regulates unfolded protein response and neuronal survival through its ER-located receptor IRE1α

V. Kovaleva, L.-Y. Yu, L. Ivanova, J. Nam, A. Eesmaa, E.-P. Kumpula, J. Huiskonen, P. Lindholm, M. H. Voutilainen, M. Karelson, M. Saarma

This study identifies MANF's mechanism of action through its interaction with IRE1α, showing it modulates UPR and protects neurons from ER stress.

bioRxiv · Sep 22, 2020 · PreprintCell Biology

Structure of herpes simplex virus pUL7:pUL51, a conserved complex required for efficient herpesvirus assembly

B. G. Butt, D. J. Owen, C. Jeffries, L. Ivanova, J. W. Houghton, M. F. Ahmed, R. Antrobus, D. I. Svergun, J. J. Welch, C. M. Crump, S. C. Graham

This paper solves the structure of the HSV-1 pUL7:pUL51 complex, showing its conservation across herpesviruses and its potential role in membrane remodeling during virus assembly.

bioRxiv · Oct 18, 2019Microbiology