Author

P. Ludzia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 5

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:protein folding & dynamics· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:mouse· 2 Assay:protein structure· 2 Organism:rat· 2

Frequent Co-Authors

B. Akiyoshi· 5 shared G. Marciano· 2 shared M. Ishii· 2 shared O. O. Nerusheva· 2 shared A. Llauro· 1 shared A. Wilson· 1 shared C. L. Asbury· 1 shared C. Redfield· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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5 shared papersCell Biology

B. Akiyoshi

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5 papers

Recent·Most cited

Kinetoplastid kinetochore proteins KKT14-KKT15 are divergent Bub1/BubR1-Bub3 proteins

D. Ballmer, W. Carter, J. J. E. van Hooff, E. C. Tromer, M. Ishii, P. Ludzia, B. Akiyoshi

This study identifies KKT14-KKT15 in kinetoplastids as divergent orthologs of Bub1/BubR1-Bub3, suggesting a unique mechanism for chromosome segregation fidelity in trypanosomes.

bioRxiv · Jan 4, 2024Cell Biology

Divergent polo boxes in KKT2 and KKT3 initiate the kinetochore assembly cascade in Trypanosoma brucei

M. Ishii, P. Ludzia, G. Marciano, W. Allen, O. O. Nerusheva, B. Akiyoshi

This study identifies KKT2 and KKT3 as kinetoplastid kinetochore proteins that use divergent polo boxes to recruit downstream proteins, essential for kinetochore assembly in Trypanosoma brucei.

bioRxiv · Jun 2, 2022Cell Biology

Structural characterisation of KKT4, an unconventional microtubule-binding kinetochore protein

P. Ludzia, E. Lowe, G. Marciano, S. Mohammed, C. Redfield, B. Akiyoshi

This study characterizes the structure and dynamics of KKT4, a kinetoplastid kinetochore protein, revealing its microtubule-binding domain and DNA-binding properties.

bioRxiv · Oct 14, 2020Cell Biology

Identification of four unconventional kinetoplastid kinetochore proteins KKT22-25 in Trypanosoma brucei

O. O. Nerusheva, P. Ludzia, B. Akiyoshi

This study identifies four new kinetochore proteins, KKT22-25, in Trypanosoma brucei and shows interactions between KKIP and KKT proteins.

bioRxiv · Sep 27, 2019Cell Biology

The unconventional kinetoplastid kinetochore protein KKT4 tracks with dynamic microtubule tips

A. Llauro, H. Hayashi, M. E. Bailey, A. Wilson, P. Ludzia, C. L. Asbury, B. Akiyoshi

This study identifies KKT4, a kinetoplastid kinetochore protein that binds and tracks with microtubule tips, enabling chromosome segregation despite lacking homology to known microtubule-binding domains.

bioRxiv · Nov 9, 2017Cell Biology