Mechanobiological Conditioning of Mesenchymal Stem Cells Enhances Therapeutic Angiogenesis by Inducing a Hybrid Pericyte-Endothelial Phenotype
J. Lee, K. Henderson, M. Armenta-Ochoa, A. Veith, P. Maceda, E. Yoon, L. Samarneh, M. Wong, A. Dunn, A. Baker
This study shows that combining mechanical strain and kinase inhibitors enhances mesenchymal stem cells to express pericyte and endothelial markers, improving their angiogenic capabilities.
bioRxiv · Dec 5, 2018 · PreprintBioengineering