A. Baker

A Computational Model of Mechanical Stretching of Cultured Cells on a Flexible Membrane

This paper develops a computational model to simulate mechanical stretching of cultured cells on a flexible membrane and connects it to chromatin deformation.

Mechanical Rejuvenation of Mesenchymal Stem Cells from Aged Patients

This study shows that mechanical conditioning improves the regenerative potential of aged mesenchymal stem cells by reducing senescence and altering their genetic landscape.

Phosphate overplus response in Chlamydomonas reinhardtii: polyphosphate dynamics to monitor phosphate uptake and turnover

This paper quantifies polyphosphate dynamics in Chlamydomonas reinhardtii during phosphate deprivation and resupply to optimize phosphate overplus response and nutrient recovery.

Colchicine promotes atherosclerotic plaque stability independently of inflammation

This study shows colchicine stabilizes atherosclerotic plaques by converting harmful SMC-derived cells into protective myofibroblast-like cells, independent of its anti-inflammatory effects.

Heart-on-a-chip model of immune-induced cardiac dysfunction reveals the involvement of free mitochondrial DNA and therapeutic effects of endothelial exosomes

This paper develops a heart-on-a-chip model to study immune-induced cardiac dysfunction, identifying mitochondrial DNA as a key factor and showing therapeutic potential of endothelial exosomes.

Inhibition of somatostatin enhances the long-term metabolic outcomes of sleeve gastrectomy in mice

This study shows that inhibiting somatostatin signaling improves and sustains metabolic benefits after sleeve gastrectomy in mice.

Transmembrane Stem Factor Nanodiscs Enhanced Revascularization in a Hind Limb Ischemia Model in Diabetic, Hyperlipidemic Rabbits

This study tests tmSCF nanodiscs in a diabetic, hyperlipidemic rabbit model of hindlimb ischemia and finds improved vascularity without inflammation.

Overexpression of PSR1 in Chlamydomonas reinhardtii induces luxury phosphorus uptake

Overexpressing PSR1 in Chlamydomonas reinhardtii increases phosphorus uptake and PolyP granule size, enabling efficient Pi removal from wastewater.

Syndecan-4 Proteoliposomes Enhance Revascularization in a Rabbit Hind Limb Ischemia Model of Peripheral Ischemia

This study shows that syndecan-4 proteoliposomes enhance blood vessel growth in a rabbit hind limb ischemia model when combined with growth factors.

The Chalcidoidea bush of life - a massive radiation blurred by mutational saturation

This study reconstructs the phylogeny of the hyperdiverse Chalcidoidea wasps, identifying classification issues and evolutionary shifts linked to angiosperm diversification.

Porous marine snow differentially benefits chemotactic, motile, and non-motile bacteria

This study shows that bacterial motility is essential for colonizing marine particles, while chemotaxis benefits at higher settling velocities, and non-motile bacteria disproportionately benefit from porous particle structures.

AusTraits: a curated plant trait database for the Australian flora

AusTraits is a curated plant trait database for the Australian flora, containing 937243 trait-by-taxa combinations across 375 traits and 29230 taxa.

Lack of evidence of ACE2 expression and replicative infection by SARS-CoV-2 in human endothelial cells

The paper investigates ACE2 expression and SARS-CoV-2 infection in human endothelial cells, finding low or absent ACE2 expression and no viral replication.

Alternative splicing liberates a cryptic cytoplasmic isoform of mitochondrial MECR that antagonizes influenza virus

The paper identifies a cryptic cytoplasmic isoform of MECR generated by alternative splicing that inhibits influenza virus replication by blocking viral RNP assembly.

Laser nanobubbles induce immunogenic cell death in breast cancer

This study shows laser-generated nanobubbles induce immunogenic cell death in breast cancer cells by increasing DAMPs and activating dendritic cells.

Transmembrane Stem Cell Factor Protein Therapeutics EnhanceRevascularization in Ischemia without Mast Cell Activation

This study develops tmSCF-based therapeutics that enhance revascularization in ischemia without activating mast cells, using proteoliposomes and lipid nanodiscs as delivery systems.

A Non-Destructive Method for Quantifying Tissue Vascularity Using Quantitative Deep Learning Image Processing

This paper introduces a non-destructive method using deep learning to quantify tissue vascularity through micro CT imaging and convolutional neural networks.

Biomechanical Regulation of Breast Cancer Metastasis and Progression

This study investigates how mechanical forces affect breast cancer cell behavior, finding that tension alters gene expression, increases chemoresistance, and promotes metastasis through specific signaling pathways.

Phenotypic differences in reversible attachment behavior reveal distinct P. aeruginosa surface colonization strategies

The paper examines reversible attachment behavior in P. aeruginosa strains PAO1 and PA14, revealing distinct surface colonization strategies through single-cell tracking and stochastic modeling.

Diverse phenotypic responses and phosphate content in foxtail millet genotypes under greenhouse and field conditions

This study analyzes phenotypic responses and phosphate content in foxtail millet genotypes under greenhouse and field conditions to identify genotypic plasticity for improved phosphorus use efficiency.

On the move: Redox-dependent protein relocation

This study investigates how redox post-translational modifications regulate protein compartmentation and relocation in eukaryotic cells.

Mechanobiological Conditioning of Mesenchymal Stem Cells Enhances Therapeutic Angiogenesis by Inducing a Hybrid Pericyte-Endothelial Phenotype

This study shows that combining mechanical strain and kinase inhibitors enhances mesenchymal stem cells to express pericyte and endothelial markers, improving their angiogenic capabilities.