Author

P. Nastaly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

N. Bednarz-Knoll· 2 shared P. Maiuri· 2 shared A. A. Mironov· 1 shared A. Ferrari· 1 shared A. Ghisleni· 1 shared A. J. Zaczek· 1 shared A. Mironov· 1 shared A. Poli· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

N. Bednarz-Knoll

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Author profile →

3 papers

Recent·Most cited

Pauperization of Emerin from nuclear envelope during chromatin bridge resolution drives prostate cancer cell migration and invasiveness

P. Nastaly, M. Popeda, K. Kowalski, T. Wenta, G. Beznoussenko, M. Rychlowski, A. Mironov, Z. Lavagnino, S. Barozzi, J. Richert, R. Bertolio, J. Szade, K. Miszewski, M. Matuszewski, A. J. Zaczek, , P. Maiuri

The paper shows that micronuclei formation during chromatin bridge resolution in prostate cancer cells leads to emerin pauperization from the nuclear envelope, enhancing cell migration and invasiveness.

bioRxiv · Nov 6, 2023 · PreprintCancer Biology

PIP4K2B is a mechanosensor and induces heterochromatin-driven nuclear softening through UHRF1.

A. Poli, F. A. Pennacchio, P. Nastaly, A. Ghisleni, M. Crestani, F. M. Pramotton, F. Iannelli, G. Beznusenko, A. A. Mironov, V. Panzetta, S. Fusco, B. Sheth, N. Paolo, D. Poulikakos, A. Ferrari, , P. Maiuri

The paper identifies PIP4K2B as a mechanosensor that induces nuclear softening via UHRF1, affecting YAP activity and cell motility in cancer.

bioRxiv · Mar 25, 2022 · PreprintCell Biology

ALDH1-positive intratumoral stromal cells indicate epithelial differentiation and good prognosis in prostate cancer

P. Nastaly, M. Filipska, C. Morrissey, E. Eltze, A. Semjonow, B. Brandt, K. Pantel, N. Bednarz-Knoll

The paper examines ALDH1 expression in prostate cancer stromal cells, finding it correlates with better prognosis and more differentiated epithelial phenotypes.

bioRxiv · Mar 5, 2018Cancer Biology