Cell BiologybioRxivPreprint
PIP4K2B is a mechanosensor and induces heterochromatin-driven nuclear softening through UHRF1.
A. Poli, F. A. Pennacchio, P. Nastaly…·P. Maiuri
The paper identifies PIP4K2B as a mechanosensor that induces nuclear softening via UHRF1, affecting YAP activity and cell motility in cancer.
DOI 10.1101/2022.03.25.485814