Author

A. Ghisleni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

M. Crestani· 3 shared N. Gauthier· 3 shared P. Maiuri· 3 shared P. Monzo· 2 shared Q. Li· 2 shared A. A. Mironov· 1 shared A. Ferrari· 1 shared A. Fukuzawa· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCell Biology

M. Crestani

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4 papers

Recent·Most cited

Mechanically induced topological transition of spectrin regulates its distribution in the mammalian cortex

A. Ghisleni, M. Bonilla-Quintana, M. Crestani, A. Fukuzawa, P. Rangamani, N. Gauthier

This study shows spectrin in mammalian cells can transition between different topological structures under mechanical stress, adapting to protect the cell cortex.

bioRxiv · Jan 2, 2023 · PreprintCell Biology

PIP4K2B is a mechanosensor and induces heterochromatin-driven nuclear softening through UHRF1.

A. Poli, F. A. Pennacchio, P. Nastaly, A. Ghisleni, M. Crestani, F. M. Pramotton, F. Iannelli, G. Beznusenko, A. A. Mironov, V. Panzetta, S. Fusco, B. Sheth, N. Paolo, D. Poulikakos, A. Ferrari, , P. Maiuri

The paper identifies PIP4K2B as a mechanosensor that induces nuclear softening via UHRF1, affecting YAP activity and cell motility in cancer.

bioRxiv · Mar 25, 2022 · PreprintCell Biology

Adaptive mechanoproperties characterize glioblastoma fitness for invasion

P. Monzo, M. Crestani, Y. K. Chong, K. Hennig, A. Ghisleni, Q. Li, C. Richichi, P. Maiuri, M. Balland, M. P. Sheetz, G. Pelicci, B. T. Ang, C. Tang, N. C. Gauthier

The paper identifies FMN1 as a driver of glioblastoma invasiveness by linking it to increased cell stiffness, mechanical forces, and stochastic motility.

bioRxiv · Jun 17, 2020Cell Biology

Mesoscale Dynamics of Spectrin and Acto-Myosin shape Membrane Territories during Mechanoresponse

A. Ghisleni, C. Galli, P. Monzo, F. Ascione, M. A. Fardin, G. Scita, Q. Li, P. Maiuri, N. Gauthier

The paper investigates how spectrin and acto-myosin cytoskeletons dynamically reorganize during mechanical challenges to support membrane territories.

bioRxiv · Dec 11, 2019Cell Biology