Cell BiologybioRxivPreprint
Reovirus infection is regulated by NPC1 and endosomal cholesterol homeostasis
P. Ortega Gonzalez, G. M. Taylor, R. Jangra…·T. S. Dermody
This study identifies NPC1 and endosomal cholesterol homeostasis as critical for reovirus penetration into the cytoplasm, but not for attachment, internalization, or disassembly.
DOI 10.1101/2021.09.27.462002