Author

P. Radvak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:CITE-seq· 1

Frequent Co-Authors

H. Xie· 4 shared M. Kosikova· 3 shared H. J. Kwon· 2 shared C. M. Boudreau· 1 shared C. Z. Chen· 1 shared F. J. Noelette· 1 shared G. Alter· 1 shared J. D. Campbell· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersImmunology

H. Xie

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mitoxantrone modulates a glycosaminoglycan-spike complex to inhibit SARS-CoV-2 infection

Q. Zhang, P. Radvak, J. Lee, Y. Xu, V. Cao-Dao, M. Xu, W. Zheng, C. Z. Chen, H. Xie, Y. Ye

This study shows Mitoxantrone inhibits SARS-CoV-2 infection by targeting the spike-GAG complex, but also affects nucleosome dynamics.

bioRxiv · Oct 15, 2021 · PreprintCell Biology

B.1.1.7 and B.1.351 variants are highly virulent in K18-ACE2 transgenic mice and show different pathogenic patterns from early SARS-CoV-2 strains

P. Radvak, H. J. Kwon, M. Kosikova, U. Ortega-Rodriguez, R. Xiang, J.-N. Phue, R.-F. Shen, J. Rozzelle, N. Kapoor, T. Rabara, J. Fairman, H. Xie

This study shows that B.1.1.7 and B.1.351 SARS-CoV-2 variants are more lethal than early strains in K18-hACE2 mice and cause distinct pathogenic effects.

bioRxiv · Jun 5, 2021Immunology

Functional and structural modifications of influenza antibodies during pregnancy

M. F. Jennewein, M. Kosikova, F. J. Noelette, P. Radvak, C. M. Boudreau, J. D. Campbell, W. H. Chen, H. Xie, G. Alter, M. F. Pasetti

This study examines how influenza antibodies change structurally and functionally during pregnancy, showing reduced inflammation and increased antibody retention.

bioRxiv · May 18, 2021Immunology

Mapping the Antibody Repertoires in Ferrets with Repeated Influenza A/H3 Infections: Is Original Antigenic Sin Really "Sinful"?

T. Einav, M. Kosikova, P. Radvak, Y.-C. Kuo, H. J. Kwon, H. Xie

This study uses a new computational tool to analyze antibody repertoires in ferrets after repeated influenza infections, finding that broadly neutralizing antibodies can emerge despite original antigenic sin.

bioRxiv · Oct 22, 2020Immunology