PathologybioRxivPreprint
APOE ε4 allele advances the age-dependent decline of amyloid β clearance in the human cortex
A. Saito, Y. Kageyama, O. Pletnikova…·J. C. Troncoso
This study shows that the APOE ε4 allele causes earlier age-related decline in amyloid β clearance in the human cortex, supporting early intervention strategies for Alzheimer's disease.