Author

P. Swuec

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:cryo-EM· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

M. Bolognesi· 2 shared A. Bharadwaj· 1 shared A. Chaves-Sanjuan· 1 shared A. J. Jakobi· 1 shared A. Paiardini· 1 shared A. Paone· 1 shared A. Parroni· 1 shared A. Tramonti· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

M. Bolognesi

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Author profile →

3 papers

Recent·Most cited

Serialized On-grid Lift-In Sectioning for Tomography (SOLIST)

P. S. Erdmann, T.-D. H. Nguyen, G. Perone, R. Vazzana, F. K. Don, M. Silva, S. Sorrentino, P. Swuec, F. Leroux, N. Kalebic, F. Coscia

The paper introduces SOLIST, a method that improves cryo-electron tomography by increasing throughput, reducing ice contamination, and enhancing sample stability for various specimens.

bioRxiv · May 11, 2023 · PreprintBiophysics

THE RIBOREGULATION MECHANISM OF HUMAN SERINE HYDROXYMETHYLTRANSFERASE IS ROOTED IN AN ALLOSTERIC SWITCH

S. Spizzichino, F. Di Fonzo, C. Marabelli, A. Tramonti, A. Chaves-Sanjuan, A. Parroni, G. Boumis, F. R. Liberati, A. Paone, L. C. Montemiglio, M. Ardini, A. J. Jakobi, A. Bharadwaj, P. Swuec, G. G. Tartaglia, , F. Cutruzzola

This study identifies an allosteric RNA switch mechanism regulating SHMT1 activity, revealing structural elements critical for RNA binding and implications for RNA-based therapies.

bioRxiv · Mar 17, 2023Biochemistry

Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain (AL) amyloidosis patient

P. Swuec, F. Lavatelli, M. Tasaki, C. Paissoni, P. Rognoni, M. Maritan, F. Brambilla, P. Milani, P. Mauri, C. Camilloni, G. Palladini, G. Merlini, S. Ricagno, M. Bolognesi

The paper reports the cryo-EM structure of cardiac amyloid fibrils from an AL amyloidosis patient, revealing key structural features of the light chain variable domain involved in fibril formation.

bioRxiv · Oct 17, 2018Biochemistry