Author

P. Tyagi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:metabolomics· 2 Organism:rat· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. K. Saini· 2 shared D. Sharma· 2 shared J. Kumar· 2 shared V. Kumar· 2 shared A. Singh· 1 shared B. Ward· 1 shared C. Griffey· 1 shared C. Sneller· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. K. Saini

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4 papers

Recent·Most cited

Analytical Method Development for Evaluation of Pharmacokinetics and Tissue Distribution of Thiourea-Based Antivirals through nLC/MS-MS

J. Kumar, P. Tyagi, A. K. Saini, D. Sharma, V. Kumar

The paper develops a sensitive nLC-MS/MS method to quantify thiourea derivatives in plasma and tissues of rats, showing good linearity and precision.

bioRxiv · Jun 28, 2023 · PreprintPharmacology & Toxicology

Safety Assessment and Evaluation of Novel Thiourea Derivatives as Antivirals

J. Kumar, P. Tyagi, a. k. saini, D. Sharma, V. Kumar

This paper evaluates the safety of three thiourea derivatives (DSA-00, DSA-02, DSA-09) as antivirals, finding they are non-cytotoxic, non-mutagenic, and have moderate acute toxicity.

bioRxiv · Jun 25, 2023 · PreprintPharmacology & Toxicology

Mycobacterium tuberculosis reactivates HIV via exosomes mediated resetting of cellular redox potential and bioenergetics

P. Tyagi, V. K. Pal, S. Srinivasan, A. Singh

This study shows that Mtb exosomes reactivate HIV-1 by altering redox potential and bioenergetics, with antioxidant and host factor inhibitors reducing reactivation.

bioRxiv · May 7, 2019Microbiology

Genome-wide association studies for yield-related traits in soft red winter wheat grown in Virginia

B. Ward, G. Brown-Guedira, F. Kolb, D. Van Sanford, P. Tyagi, C. Sneller, C. Griffey

This study performs GWAS on yield-related traits in soft red winter wheat using SNP data from GBS, identifying 74 significant marker-trait associations with FarmCPU.

bioRxiv · Nov 15, 2018Plant Biology