Author

P. Vail

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Witkiewicz· 2 shared E. Knudsen· 2 shared A. Grant· 1 shared A. Ruiz· 1 shared J. Wang· 1 shared M. Padi· 1 shared M. Seshadri· 1 shared S. Abrams· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

A. Witkiewicz

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2 papers

Recent·Most cited

Targeting dual signaling pathways in concert with immune checkpoints for the treatment of pancreatic cancer

E. Knudsen, V. Kumarasamy, S. Chung, P. Vail, S. Tzetzo, A. Ruiz, M. Seshadri, S. Abrams, J. Wang, A. Witkiewicz

This study shows that combining MEK and CDK4/6 inhibitors with immune checkpoint inhibitors improves pancreatic cancer treatment by enhancing T-cell infiltration and altering myeloid populations in preclinical models.

bioRxiv · Dec 5, 2019Cancer Biology

Interrogating Mutant Allele Expression via Customized Reference Genomes to Define Influential Cancer Mutations

A. Grant, P. Vail, M. Padi, A. Witkiewicz, E. Knudsen

The paper introduces MAXX, a tool to analyze allelic expression of mutations in cancer, identifying driver mutations and prognostic subtypes in PDAC.

bioRxiv · Aug 17, 2018Cancer Biology