ImmunologybioRxivPreprint
Adaptive anti-tumor immunity is orchestrated by a population of CCL5-producing tissue-resident NK cells
N. Kirchhammer, M. P. Trefny, M. Natoli…·A. Zippelius
The paper shows that CCL5-producing tissue-resident NK cells are critical for IL-12-mediated anti-tumor immunity and that CCL5 delivery can overcome resistance in tumors with low trNK cell infiltration.