Author

P.-i. Ku

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

R. Subramanian· 2 shared A. B. Long· 1 shared A. Lee· 1 shared A. Poddar· 1 shared B. R. Myers· 1 shared C. D. Arveseth· 1 shared C. Freniere· 1 shared E. M. Wilson-Kubalek· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

R. Subramanian

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Author profile →

2 papers

Recent·Most cited

GRK2 Kinases in the Primary Cilium Initiate SMOOTHENED-PKA Signaling in the Hedgehog Cascade

M. F. Walker, J. Zhang, W. Steiner, P.-I. Ku, J.-F. Zhu, Z. Michaelson, Y.-C. Yen, A. Lee, A. B. Long, M. J. Casey, A. Poddar, I. B. Nelson, C. D. Arveseth, F. Nagel, R. Clough, , B. R. Myers

This study identifies GRK2-mediated phosphorylation of SMO in the primary cilium as a critical step initiating SMO-PKA signaling in the Hedgehog pathway.

bioRxiv · May 10, 2023Cell Biology

Cytoskeletal regulation of a transcription factor by DNA mimicry

F. Haque, C. Freniere, Q. Ye, N. Mani, E. M. Wilson-Kubalek, P.-i. Ku, R. A. Milligan, R. Subramanian

The paper reveals DNA mimicry by Kif7 as a mechanism for recruiting Gli transcription factors to microtubules, showing it can be used to inhibit Gli localization in cancer.

bioRxiv · Sep 30, 2021 · PreprintCell Biology