Neoantigen-driven B cell and CD4+ T follicular helper cell collaboration promotes robust anti-tumor CD8+ T cell responses
C. Cui, J. Wang, P.-M. Chen, K. A. Connolly, M. Damo, E. Fagerberg, S. Chen, S. C. Eisenbarth, H. Zhao, J. Craft, N. S. Joshi
This study shows that TFH-B cell interactions driven by neoantigens enhance anti-tumor CD8+ T cell responses in lung adenocarcinoma.
bioRxiv · Dec 23, 2020Immunology