Patricia B. Gordon

This study shows that viscous mechanical cues influence cancer cell metastasis through cytoskeletal-nuclear coupling and chromatin remodeling.

The paper uses intravital imaging in zebrafish to show age-dependent changes in collective T cell migration patterns in fins, linking tissue structure and immune function.

The paper uses optical tweezers and Brillouin microscopy to study brain mechanical properties in larval zebrafish, showing macrophages influence tissue mechanics during development.

The paper examines organ-specific microenvironmental MR1 expression in cutaneous melanoma using zebrafish models and imaging techniques, finding differential immune responses and metabolism in brain versus skeletal metastases.

This study investigates how YAP-mediated mechanogenotypes influence mechanical adaptation of cancer cells during extravasation and organ colonization in vivo.