Philip K Maini

The paper identifies a minimal signaling model that explains T cell responses across a wide range of antigen affinity and dose variations.

This paper uses a computational model to show that spatial organization of blood vessels in tumors affects radiation response, with varying correlations depending on vessel density.

This paper develops a Markov Chain model to analyze antibiotic resistance emergence in E. coli and shows that drug sequencing can probabilistically steer populations away from resistance.

This paper proposes a physical network model of CTC flow to predict metastatic patterns and improve staging of oligometastatic disease.

This paper develops a spatial mathematical model of glucose-lactate metabolism in tumors and finds that metabolic symbiosis is robust and may enhance oxygenation, suggesting potential for targeted therapy.