ImmunologybioRxiv
Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization
Rajesh P. Ringe, Philippe Colin, Gabriel Ozorowski…·P. J. Klasse
This study investigates how glycan heterogeneity on HIV-1 Env contributes to persistent infectivity despite neutralizing antibody (NAb) treatment, showing that glycan variants affect antibody binding and neutralization efficacy.
DOI 10.1371/journal.ppat.1011601