Aleksandar Antanasijevic

This study characterizes polyclonal antibody responses to RSV and hMPV fusion proteins, revealing shared and distinct antigenic features that may inform vaccine design.

This study examines how mutations in the N-terminal domain of SARS-CoV-2 Spike affect antigenic properties and immune escape, finding that structural flexibility and loss of heme-metabolite interaction reduce antibody neutralization.

This study identifies two antibody classes that neutralize pneumovirus by targeting a conserved epitope, revealing distinct mechanisms of action through structural and functional analyses.

This study uses cryoEM and machine learning to predict and redirect immunodominant epitopes in HIV Env, showing improved vaccine antigen design.

This study shows that structural flexibility in computationally designed protein assemblies leads to multiple architectures, expanding their functional possibilities.

The paper identifies anti-immune complex antibodies generated through repeated HIV Env immunizations and presents their structures using polyclonal epitope mapping.

This study shows that EV-A71 adapts to heparan sulfate by losing pH-dependent uncoating, which compromises capsid stability and affects viral fitness in vivo.

This study investigates how amino acid substitutions in coxsackievirus B5 capsid proteins affect sensitivity to free chlorine and heat, finding that capsid changes have a minor role in chlorine sensitivity but reduce heat sensitivity in specific mutants.

The paper investigates missense mutations in PREPL in CMS22 patients, showing they affect non-hydrolytic functions without impairing hydrolase activity.

This study investigates how glycan heterogeneity on HIV-1 Env contributes to persistent infectivity despite neutralizing antibody (NAb) treatment, showing that glycan variants affect antibody binding and neutralization efficacy.

Designed trimers matched to viral glycoprotein termini yielded tetrahedral, octahedral and icosahedral nanoparticles with cryo-EM-verified structures that display native-like HIV Env, influenza HA and RSV F.