Cancer BiologybioRxivPreprint
The BRD4S-LOXL2-MED1 interaction at the forefront of cell cycle transcriptional control in triple-negative breast cancer
L. Pascual-Reguant, T. V. Tian, D. Datta…·S. Sdelci
This study shows that inhibiting LOXL2 and BRD4 together reduces triple-negative breast cancer proliferation by disrupting the BRD4S-LOXL2-MED1 interaction that controls cell cycle gene expression.
DOI 10.1101/2022.05.27.493725