Cell BiologyPLoS BiologyPeer-reviewed
Oxaloacetate damages mitochondria by perturbing MIC60-dependent membrane remodeling
J. Jillian Zhang, Qian Shan, Xin Wang…·Chonglin Yang
The paper identifies oxaloacetate accumulation as a cause of mitochondrial damage by inhibiting MIC60-dependent membrane remodeling in C. elegans and mammalian cells.
DOI 10.1371/journal.pbio.3003649