Author

P.-G. Coulon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:flow cytometry· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

L. BenMohamed· 5 shared S. Prakash· 5 shared N. Dhanushkodi· 4 shared R. Srivastava· 4 shared A. Quadiri· 2 shared H. Vahed· 2 shared L. Zayou· 2 shared A. A. Chentoufi· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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5 shared papersImmunology

L. BenMohamed

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Author profile →

5 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 26, 2022

High Frequencies of Phenotypically and Functionally Senescent and Exhausted CD56+CD57+PD-1+ Natural Killer Cells, SARS-CoV-2-Specific Memory CD4+ and CD8+ T cells Associated with Severe Disease in Unvaccinated COVID-19 Patients

L. BenMohamed, R. Srivastava, N. Dhanushkodi…·A. Quadiri

This study identifies increased exhaustion and senescence markers in NK and T cells of unvaccinated symptomatic COVID-19 patients, correlating with severe disease.

DOI 10.1101/2022.07.26.501655

humanflow cytometry

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ImmunologybioRxivPreprintJul 22, 2022

A Prime/Pull RR2/CXCL11 Therapeutic Vaccine that Bolsters the Number and Function of Dorsal Root Ganglia Tissue-Resident HSV-Specific CD8+ TRM Cells Protects Latently Infected Guinea Pigs from Recurrent Genital Herpes

N. Dhanushkodi, S. Prakash, R. Srivastava…·L. BenMohamed

This study develops a prime/pull vaccine using RR2 and CXCL11 to increase tissue-resident CD8+ TRM cells, reducing HSV-2 reactivation and genital herpes severity in guinea pigs.

DOI 10.1101/2022.07.22.501208

experimental assayhost-pathogen & immune response

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ImmunologyJournal of VirologyPeer-reviewedMar 9, 2022

Antiviral CD19+CD27+ Memory B Cells Are Associated with Protection from Recurrent Asymptomatic Ocular Herpes Infection

N. Dhanushkodi, S. Prakash, R. Srivastava…·L. BenMohamed

The paper identifies increased frequencies of HSV-specific memory B cells in asymptomatic individuals and mice, correlated with memory Tfh cells, suggesting their role in protection against recurrent ocular herpes.

DOI 10.1128/jvi.02057-21

humanmouse

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ImmunologybioRxivNov 25, 2020

Healing of Primary and Recurrent Mouse Ocular Herpetic Disease Following Topical Ocular Treatment with an Engineered Fibroblast Growth Factor-1 (FGF-1) is Associated with Increased Frequency and Function of Corneal Anti-Inflammatory M2 Macrophages

N. Dhanushkodi, R. Srivastava, P.-G. Coulon…·L. BenMohamed

This study shows that engineered FGF-1 (TTHX1114) reduces HSV-1-induced corneal disease in mice by increasing anti-inflammatory M2 macrophages and decreasing pro-inflammatory M1 macrophages.

DOI 10.3389/fimmu.2021.673763

mouseproteomics

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ImmunologybioRxivSep 27, 2020

Genome-Wide Asymptomatic B-Cell, CD4+ and CD8+ T-Cell Epitopes, that are Highly Conserved Between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Immune Targets for Pre-Emptive Pan-Coronavirus Vaccines

S. Prakash, S. Ruchi, P.-G. Coulon…·L. BenMohamed

The paper identifies conserved B-cell and T-cell epitopes across multiple Coronaviruses to inform the development of a pan-Coronavirus vaccine.

DOI 10.4049/jimmunol.2001438

humanmouse

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