BiochemistrybioRxiv
Distinct stimulatory mechanisms regulate the catalytic activity of Polycomb Repressive Complex 2 (PRC2)
C.-H. Lee, M. Holder, D. Grau…·K.-J. Armache
The paper shows that EZH1 and EZH2, two catalytic subunits of PRC2, are differentially activated to regulate H3K27 methylation, with AEBP2 adding additional stimulation.
DOI 10.1016/j.molcel.2018.03.019