BioengineeringbioRxiv
Detection of low numbers of bacterial cells in pharmaceutical drug product using Raman Spectroscopy and PLS-DA multivariate analysis.
R. A. Grosso, A. R. Walther, E. Brunbech…·E. C. Arnspang
This study detects bacterial contamination in drug products below 10 CFU/ml using Raman spectroscopy and PLS-DA, achieving 99% accuracy.
DOI 10.1039/d2an00683a