Cancer BiologybioRxiv
Polyamine transport inhibition and cisplatin synergistically enhance tumor control through oxidative stress in murine head and neck cancer models
A. Yassin-Kassab, N. Wang, J. R. Foley…·U. Duvvuri
This study shows that combining cisplatin with AMXT-1501 enhances tumor control in HNSCC models by increasing oxidative stress and apoptosis, independent of polyamine levels.
DOI 10.1016/j.oor.2023.100123