Author

R. Akhurst

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Balmain· 2 shared D. Beleford· 1 shared D. Quigley· 1 shared D. Wu· 1 shared E. Kandyba· 1 shared H. Goodarzi· 1 shared J. Zhang· 1 shared K. Halliwell· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

A. Balmain

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Gene networks reveal stem-cell state convergence during preneoplasia and progression to malignancy in multistage skin carcinogenesis

M. A. Taylor, E. Kandyba, K. Halliwell, R. Del Rosario, M. S. Khoroshkin, H. Goodarzi, D. Quigley, Y. R. Li, D. Wu, S. Bollam, O. Mirzoeva, R. Akhurst, A. Balmain

The paper identifies gene networks driving cancer progression by analyzing stem-cell states in mouse skin carcinogenesis and links them to drug resistance and immune surveillance in human tumors.

bioRxiv · May 8, 2023 · PreprintCancer Biology

PTPN14, a modifier of HHT, protects SMAD4 from ubiquitination and turnover to potentiate BMP9 signaling in endothelial cells.

O. MAMAI, D. Beleford, M. Taylor, S. Basu, X. Cen, S. Trilok, J. Zhang, A. Balmain, R. Akhurst

This study identifies PTPN14 as a stabilizer of SMAD4, enhancing BMP9 signaling in endothelial cells and suggesting potential drug targets for HHT.

bioRxiv · Sep 29, 2021 · PreprintCell Biology