Author

R. Bos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:protein structure· 1 Organism:zebrafish· 1

Frequent Co-Authors

H. Schuitemaker· 3 shared J. Custers· 3 shared D. Zuijdgeest· 2 shared F. Wegmann· 2 shared J. Juraszek· 2 shared J. P. Langedijk· 2 shared L. Muchene· 2 shared R. Vogels· 2 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersImmunology

H. Schuitemaker

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Author profile →

4 papers

Recent·Most cited

Immunogenicity of an Ad26-based SARS-CoV-2 Omicron Vaccine in Naïve Mice and SARS-CoV-2 Spike Pre-immune Hamsters

M. Swart, A. de Wilde, S. Schmit-Tillemans, J. Verspuij, C. Daal, Y. Choi, A. Perkasa, E. Kourkouta, I. Tahiri, M. Mulders, A. I. Gil, L. Muchene, J. Juraszek, J. Vellinga, J. Custers, , R. Zahn

This study evaluates an Ad26-based Omicron spike vaccine in mice and pre-immune hamsters, showing it induces neutralizing antibodies against Omicron and Delta variants.

bioRxiv · Mar 4, 2022 · PreprintImmunology

Ad26.COV2.S elicited neutralizing activity against Delta and other SARS-CoV-2 variants of concern

M. Jongeneelen, K. Kaszas, D. Veldman, J. Huizingh, R. van der Vlugt, T. Schouten, D. Zuijdgeest, T. Uil, G. van Roey, N. Guimera, M. Navis, R. Bos, M. Le Gars, J. Sadoff, L. Muchene, , B. Brandenburg

This study evaluates the neutralizing activity of Ad26.COV2.S vaccine sera against SARS-CoV-2 variants, finding reduced effectiveness against Beta and Gamma but less reduction against Delta.

bioRxiv · Jul 1, 2021 · PreprintImmunology

Ad26-vector based COVID-19 vaccine encoding a prefusion stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

R. Bos, L. Rutten, J. E. M. van der Lubbe, M. J. G. Bakkers, G. Hardenberg, F. Wegmann, D. Zuijdgeest, A. H. de Wilde, A. Koornneef, A. Verwilligen, D. van Manen, T. Kwaks, R. Vogels, T. J. Dalebout, S. K. Myeni, , H. Schuitemaker

This paper evaluates a prefusion-stabilized SARS-CoV-2 Spike protein vaccine candidate, Ad26.COV2.S, showing potent neutralizing and Th1-polarized immune responses in mice.

bioRxiv · Jul 30, 2020Immunology

EVALUATION OF OSTEOINDUCTIVITY OF DIFFERENT CALCIUM PHOSPHATE AND PTMC-CALCIUM PHOSPHATE COMPOSITE BIOMATERIALS IN A SHEEP MODEL

A. van Arnhem, N. Zeng, A. van Leeuwen, R. Kuijer, R. Bos, D. Grijpma

This study evaluates the osteoinductive potential of various calcium phosphate and PTMC-calcium phosphate composite biomaterials in a sheep model, finding that BCP particles and β-TCP scaffolds induce new bone formation.

bioRxiv · Jun 10, 2019 · PreprintBioengineering