Author

N. Guimera

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Scientific Communication & Education· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:benchmarking· 2 Research Focus:host-pathogen & immune response· 2 Assay:whole-genome sequencing· 2 Research Focus:database / resource· 1 Organism:rat· 1 Research Focus:software / tool· 1

Frequent Co-Authors

H. Schuitemaker· 2 shared J. Sadoff· 2 shared M. Le Gars· 2 shared R. Mazumder· 2 shared A. Bell· 1 shared A. Chandrashekar· 1 shared A. Hayes· 1 shared A. Purkayastha· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

H. Schuitemaker

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Ad26.COV2.S elicited neutralizing activity against Delta and other SARS-CoV-2 variants of concern

M. Jongeneelen, K. Kaszas, D. Veldman, J. Huizingh, R. van der Vlugt, T. Schouten, D. Zuijdgeest, T. Uil, G. van Roey, N. Guimera, M. Navis, R. Bos, M. Le Gars, J. Sadoff, L. Muchene, , B. Brandenburg

This study evaluates the neutralizing activity of Ad26.COV2.S vaccine sera against SARS-CoV-2 variants, finding reduced effectiveness against Beta and Gamma but less reduction against Delta.

bioRxiv · Jul 1, 2021 · PreprintImmunology

SARS-CoV-2 binding and neutralizing antibody levels after vaccination with Ad26.COV2.S predict durable protection in rhesus macaques

R. Roozendaal, L. Solforosi, D. Stieh, J. Serroyen, R. Straetemans, F. Wegmann, S. K. Rosendahl Huber, J. E. M. van der Lubbe, J. Hendriks, M. le Gars, L. Dekking, D. N. Czapska-Casey, N. Guimera, S. Janssen, S. Tete, , R. Zahn

This study shows that Ad26.COV2.S vaccine provides long-lasting protection in rhesus macaques, predicted by binding and neutralizing antibody levels against SARS-CoV-2.

bioRxiv · Jan 30, 2021Immunology

Communicating Regulatory High Throughput Sequencing Data Using BioCompute Objects

C. H. S. King, J. G. Keeney, N. Guimera, S. Das, R. Mazumder, B. Fochtman, S. Telawar, J. Patel, M. O. Walderhaug, E. F. Donaldson

The paper demonstrates that BioCompute Objects (BCOs) enable high concordance (99.15%) in replicating NGS analysis results across simulated regulatory submissions and reviews.

bioRxiv · Dec 7, 2020Scientific Communication & Education

Enabling Precision Medicine via standard communication of NGS provenance, analysis, and results

G. Alterovitz, D. A. Dean, C. Goble, M. R. Crusoe, S. Soiland-Reyes, A. Bell, A. Hayes, A. Suresh, A. Purkayastha, C. H. H. King, D. Taylor, E. Johanson, E. E. Thompson, E. Donaldson, H. Morizono, , R. Mazumder

The paper introduces the BioCompute framework to standardize genomic data reporting, enabling reproducibility and interoperability in precision medicine.

bioRxiv · Nov 5, 2018Scientific Communication & Education