Author

R. Buettner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

D. Vorholt· 2 shared M. Krueger· 2 shared A. Bansal· 1 shared A. C. Beielstein· 1 shared A. Villasenor· 1 shared B. Schumacher· 1 shared C. Barbas· 1 shared C. P. Pallasch· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

D. Vorholt

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pentose Phosphate Pathway Inhibition activates Macrophages towards phagocytic Lymphoma Cell Clearance

A. C. Beielstein, E. Izquierdo, S. J. Blakemore, N. Nickel, M. Michalik, S. Chawan, R. Brinker, H.-H. Bartel, D. Vorholt, J. L. Nolte, R. Linke, C. R. Costa Picosi, J. Saiz, F. Picard, J. Meinel, , C. P. Pallasch

This study shows that inhibiting the pentose phosphate pathway enhances macrophage phagocytosis of lymphoma cells and improves survival in a mouse model.

bioRxiv · Jun 9, 2023 · PreprintCancer Biology

NEMO- and RelA-dependent NF-kB Signaling Promotes Small Cell Lung Cancer

L. Koerner, T.-P. Yang, M. Schmiel, M. Peifer, R. Buettner, M. Pasparakis

This study identifies the role of NEMO- and RelA-dependent NF-κB signaling in promoting small cell lung cancer and suggests it as a therapeutic target.

bioRxiv · Jul 29, 2022Cancer Biology

ATM-mediated DNA damage response in macrophages primes phagocytosis and immune checkpoint regulation

A. Bansal, R. Neuhaus, E. Izquierdo-Alvarez, H. Nolte, D. Vorholt, H. Feldkoetter, P. Lohneis, R. Buettner, M. Krueger, C. Pallasch, B. Schumacher

The paper shows that DNA damage in macrophages increases PD-L1 expression and phagocytic activity, suggesting a role in chemotherapy response and immune checkpoint regulation.

bioRxiv · Mar 14, 2020 · PreprintImmunology