Author

R. C. Cheng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:E. coli· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

M. Maduke· 2 shared A. Koehl· 1 shared A. Krishnamoorti· 1 shared E. Tajkhorshid· 1 shared H. S. Mchaourab· 1 shared I. I. Mathews· 1 shared R. A. Stein· 1 shared R. J. Durham· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

M. Maduke

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintSep 7, 2020

Single-molecule FRET monitors CLC transporter conformation and subunit independence

R. C. Cheng, A. Krishnamoorti, V. Berka…·M. Maduke

This study uses smFRET to monitor CLC-ec1 conformational changes and shows subunit independence in transport.

DOI 10.1101/2020.09.07.286831

E. colifluorescence / live-cell microscopy

𝕏 PostBluesky

BiophysicsbioRxivNov 27, 2019

Structural characterization of an intermediate reveals a unified mechanism for the CLC Cl-/H+ transport cycle

T. S. Chavan, R. C. Cheng, T. Jiang…·M. Maduke

The paper presents a 2.6 Å structure of a CLC mutant, revealing a global conformational change that supports a unified transport mechanism for CLC proteins.

DOI 10.7554/elife.53479

structural biologyexperimental assay

𝕏 PostBluesky