Author

R. Cole

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. C. Lewis· 1 shared A. E. Tron· 1 shared A. J. Rogers· 1 shared A. S. Trigos· 1 shared A.-M. Girard· 1 shared B. Abrams· 1 shared B. Bowring· 1 shared B. Nicolay· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. C. Lewis

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Tissue-Like 3D Standard and Protocols for Microscope Quality Management

B. Abrams, T. Pengo, T. L. Wee, R. C. Deagle, N. Vuillemin, L. M. Callahan, M. A. Smith, K. E. Kubow, A.-M. Girard, J. Z. Rappoport, C. J. Bayles, L. A. Cameron, R. Cole, C. M. Brown

The paper introduces a 3D tissue-like standard for fluorescence microscope quality assessment, showing reproducible results across labs and equipment.

bioRxiv · Aug 14, 2022Cell Biology

Inhibition of mutant IDH1 promotes cycling of acute myeloid leukemia stem cells

E. Gruber, J. So, A. C. Lewis, R. Franich, R. Cole, L. G. Martelotto, A. J. Rogers, E. Vidacs, P. Fraser, K. Stanley, L. Jones, A. S. Trigos, N. Thio, J. Li, B. Nicolay, , L. M. Kats

This study shows that inhibiting mutant IDH1 in AML promotes leukemic stem cell cycling and sensitizes the disease to azacitidine, suggesting a combination therapy approach.

bioRxiv · Apr 6, 2022Cancer Biology

K. pneumoniae ST258 genomic variability and bacteriophage susceptibility

C. Venturini, N. Ben Zakour, B. Bowring, S. Morales, R. Cole, Z. Kovach, S. Branston, E. Kettle, N. Thomson, J. Iredell

The paper characterizes genomic variability in K. pneumoniae ST258 isolates and identifies phage susceptibility patterns, showing that effective phage therapy requires diverse phages targeting different capsule variants.

bioRxiv · May 5, 2019 · PreprintMicrobiology