Cancer BiologybioRxivPreprint
Regulation of KRAS4A/B splicing in cancer stem cells by the RBM39 splicing complex.
W.-C. Chen, M. D. To, P. M. K. Westcott…·A. Balmain
This study identifies KRAS4A and KRAS4B splice isoforms with distinct expression patterns in cancer stem cells and shows that targeting KRAS4A splicing is a potential therapeutic strategy in KRAS mutant tumors.
DOI 10.1101/646125