Author

R. Derking

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Ward· 2 shared A. Yasmeen· 2 shared G. Ozorowski· 2 shared J. P. Moore· 2 shared J. van Schooten· 2 shared K. Sliepen· 2 shared P. J. Klasse· 2 shared R. W. Sanders· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiochemistry

A. Ward

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Germline-targeting SOSIP trimer immunization elicits precursor CD4 binding-site targeting broadly neutralizing antibodies in infant macaques.

A. N. Nelson, X. Shen, S. Venkatayogi, S. Zhang, G. Ozorowski, M. Dennis, L. M. Sewall, E. Milligan, D. Davis, K. Cross, Y. Chen, J. van Schooten, J. Eudaily, J. Isaac, S. Memon, , S. R. Permar

This study shows that a multi-dose immunization with germline-targeting SOSIP vaccines induces precursor broadly neutralizing antibodies in infant macaques, similar to adult responses.

bioRxiv · Nov 7, 2023 · PreprintImmunology

Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike

R. Derking, J. D. Allen, C. Cottrell, K. Sliepen, G. E. Seabright, W.-H. Lee, K. Rantalainen, A. Antanasijevic, J. Copps, A. Yasmeen, P. van der Woude, S. W. de Taeye, T. L. G. M. van den Kerkhof, P. J. Klasse, G. Ozorowski, , R. W. Sanders

The paper modifies HIV-1 Env trimers to increase glycan occupancy and reduce artificial glycan holes, improving vaccine antigen design.

bioRxiv · Jul 2, 2020Biochemistry

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

P. Brouwer, T. Caniels, K. van Straten, J. Snitselaar, Y. Aldon, S. Bangaru, J. Torres, N. Okba, M. Claireaux, G. Kerster, A. Bentlage, M. van Haaren, D. Guerra, J. Burger, E. Schermer, , M. van Gils

This study isolates potent neutralizing antibodies from COVID-19 patients that target multiple sites on the SARS-CoV-2 spike protein, offering insights for vaccine design and therapeutic development.

bioRxiv · May 12, 2020Microbiology