Author

R. Dodean

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

J. S. Doggett· 3 shared M. K. Riscoe· 3 shared R. W. Winter· 3 shared S. Pou· 3 shared A. Nilsen· 2 shared I. Renard· 2 shared J. E. Chiu· 2 shared P. Singh· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersMicrobiology

J. S. Doggett

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Author profile →

3 papers

Recent·Most cited

Babesia duncani as a model organism to study the development, virulence and drug susceptibility of intraerythrocytic parasites in vitro and in vivo

C. Mamoun, A. C. Pal, I. Renard, P. Singh, P. Vydyam, J. E. Chiu, S. Pou, R. W. Winter, R. Dodean, L. Frueh, A. C. Nilsen, M. K. Riscoe, J. S. Doggett

This paper establishes a new in vitro and in vivo model using Babesia duncani to study parasite development, virulence, and drug susceptibility, identifying effective new therapies.

bioRxiv · Dec 1, 2021Microbiology

Effective Therapy Targeting Cytochrome bc1 Prevents Babesia Erythrocytic Development and Protects from Lethal Infection

J. E. Chiu, I. Renard, A. Chattopadhyay Pal, P. Singh, P. Vydyam, J. Thekkiniath, M. Kumar, S. Gihaz, S. Pou, R. W. Winter, R. Dodean, A. Nilsen, M. K. Riscoe, J. S. Doggett, C. Ben Mamoun

This study identifies an effective ELQ prodrug that prevents Babesia erythrocytic development and protects against lethal infection in mouse models.

bioRxiv · Mar 31, 2021Microbiology

Orally Bioavailable Endochin-like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts

J. S. Doggett, T. L. Schultz, A. Miller, I. Bruzual, S. Pou, R. W. Winter, R. Dodean, L. N. Zakharov, A. Nilsen, M. K. Riscoe, V. B. Carruthers

This study develops an orally bioavailable prodrug of ELQ-316 that enhances its plasma concentrations and efficacy against Toxoplasma gondii infection.

bioRxiv · Mar 19, 2020Pharmacology & Toxicology