R. Eisenhofer

The paper compares short-read, HiFi long-read, and hybrid sequencing strategies for genome-resolved metagenomics, finding each excels in different metrics like assembly quality, bin refinement, and mapping rate.

The paper reanalyzes ancient DNA data from Neanderthal dental calculus to challenge the claim that Neanderthals consumed the moss Physcomitrium patens, showing the result is likely due to methodological misinterpretation.

This study examines laboratory contamination in low-biomass samples over time, finding that contaminants vary by lab, season, and extraction method, and recommends controls and reporting to mitigate their impact.